Breast Cancer in a Male with BRCA2 Mutation: Is Screening Mammography Necessary in Men?
نویسنده
چکیده
We present the case of a 76 year-old male with BRCA2 and a personal history of left-sided breast cancer who presented 20 years later with right-sided breast cancer found on screening mammography. The role of screening mammography and its relevance to males with breast cancer is poorly understood. There are currently no screening guidelines for male breast cancer. Further research is needed to determine the benefit of screening males at higher risk of developing breast cancer. Jessica L. Buicko*, Michael A. Lopez and Beth Ann Lesnikoski Department of General Surgery, University of MiamiRegional Medical Campus, USA
منابع مشابه
Minor role of BRCA2 mutation (Exon2 and Exon11) in patients with early-onset breast cancer amongst Iranian Azeri-Turkish women
Objective(s): Breast cancer is the most common cancer in women. Every year, one million new cases are reported worldwide, representing 18% of the total number of cancer in women. Hereditary BRCA1 and BRCA2 mutations account for about 60% of inherited breast cancer and are the only known causes of hereditary breast cancer syndrome. The aim of this study was to determine the frequency of BRCA2 (e...
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BACKGROUND The addition of annual MRI screening to mammography has heightened optimism that intensive screening along with improved treatments may substantially improve life expectancy of women at high risk of breast cancer. However, survival data from BRCA2 mutation carriers undergoing intensive combined breast screening are scarce. METHODS We have collated the results of screening with eith...
متن کاملMutation Screening of BRCA Genes in 10 Iranian Males with Breast Cancer
Male breast cancer is a rare disease with an increasing trend. Due to limited information especially about the genetic basis of the disease in Iran and the lower age of its onset, the disease requires more attention. The aim of this study was to screen the male patients with breast cancer for BRCA mutations as well as tissue markers of estrogen receptor (ER), progesterone receptor (PR), human e...
متن کاملجهش های ژنتیکی جدید در ژن های اصلی سرطان پستان (BRCA1/BRCA2) در زنان ایرانی مبتلا به سرطان پستان زودرس
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Many factors including genetic, environmental, and acquired are involved in breast cancer development across various societies. Among all of these factors in families with a history of breast cancer throughout several generations, genetics, like predisposing genes to develop this disease, should be considered more. Early detection of mutation carriers in these genes, in turn, can play an import...
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تاریخ انتشار 2017